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Does the % of clobenzorex metabolized into amphetamine vary randomly? There is high individual variance in pharmacokinetics, and even more so with a prodrug. As far as I'm aware, there is little information about the metabolic pathway of clobenzorex. You might have some luck looking into benzphetamine as it also undergoes N-debenzylation.

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Described as amphetamine-like due to their structural and stimulant similarities, clobenzorex is one of the five most-commonly used drugs in Mexico for the treatment of obesity. Various studies have shown that amphetamines induce dopaminergic neurotoxicity and neuroinflammation in the striatum, symp …

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